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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A research laboratory is investigating the mechanism of action of a novel antiviral drug against herpes simplex virus. The drug is found to inhibit the viral DNA polymerase. Which of the following commercially available antiviral agents has a similar mechanism of action?

A) Interferon-alpha
B) Amantadine
C) Oseltamivir
D) Acyclovir

2. A microbiology laboratory is processing a sputum sample from a patient with chronic cough and night sweats.
After Ziehl-Neelsen staining, acid-fast bacilli are observed. Culture on Lowenstein-Jensen medium is positive after several weeks. Drug susceptibility testing reveals resistance to isoniazid and rifampin. This patient is MOST likely infected with:

A) Actinomyces israelii
B) Nocardia asteroides
C) Multidrug-resistant Mycobacterium tuberculosis
D) Mycobacterium avium complex

3. An acid-fast bacillus isolate recovered from a respiratory specimen after 3 weeks of incubation on Löwenstein- Jensen medium is initially non-pigmented when grown in the dark. After exposure to light for several hours, the colonies develop a distinct yellow-orange pigment. This organism is classified as a:

A) Photochromogen
B) Nonchromogen
C) Rapid grower
D) Scotochromogen

4. A patient undergoing chemotherapy for leukemia develops a severe pneumonia. Bronchoalveolar lavage fluid is examined, revealing numerous cysts containing crescent-shaped structures upon silver staining. The patient's CD4+ T-cell count is significantly low. The MOST likely diagnosis is infection with:

A) Pneumocystis jirovecii
B) Coccidioides immitis
C) Histoplasma capsulatum
D) Blastomyces dermatitidis

5. A patient develops a febrile illness with jaundice and dark urine after receiving a blood transfusion.
Laboratory testing reveals an elevated level of unconjugated bilirubin and a positive direct Coombs test.
Serological testing is positive for antibodies against a protozoan parasite that infects erythrocytes. The MOST likely causative agent is:

A) Toxoplasma gondii
B) Plasmodium falciparum
C) Trypanosoma cruzi
D) Babesia microti

Solutions: