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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

1. A key virulence factor of Neisseria meningitidis that plays a major role in immune evasion and is the target for serogrouping is the:

A) Polysaccharide capsule
B) Pili
C) IgA protease
D) Lipooligosaccharide (LOS) endotoxin

2. A microbiology laboratory receives a wound swab from a patient with a chronic, non-healing ulcer. Culture yields a Gram-positive, branching filamentous bacterium that is partially acid-fast. The MOST likely genus is:

A) Streptomyces
B) Mycobacterium
C) Nocardia
D) Actinomyces

3. A research team is investigating the development of a novel vaccine against influenza virus. They are focusing on conserved epitopes within the hemagglutinin (HA) and neuraminidase (NA) proteins to elicit broadly neutralizing antibodies. Which of the following approaches is MOST likely to achieve this goal?

A) Developing a live-attenuated influenza vaccine containing multiple serotypes.
B) Administering high doses of inactivated influenza vaccine annually.
C) Designing a subunit vaccine that presents highly variable regions of HA and NA.
D) Utilizing a recombinant viral vector to deliver conserved epitopes of HA and NA.

4. A patient with a history of travel to an area endemic for schistosomiasis presents with hematuria. Microscopic examination of a urine sediment reveals a large oval egg with a prominent terminal spine. The MOST likely causative agent is:

A) Schistosoma mansoni
B) Schistosoma japonicum
C) Schistosoma haematobium
D) Schistosoma mekongi

5. A traveler returning from Southeast Asia presents with fever, headache, and a maculopapular rash that started on the trunk and spread to the extremities, including the palms and soles. Serological testing is positive for Orientia tsutsugamushi. The vector responsible for transmitting this organism is a:

A) Flea
B) Mosquito
C) Tick
D) Mite (chigger)

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